Magic bullet baby food
Baby Bullet Vs Magic Bullet - A Complete Guide
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Baby Bullet vs Magic Bullet
Baby bullet vs magic bullet baby food maker, which one is right for you? This perfect comparison of baby bullet vs magic bullet will tell you everything you need to know. Space is small, but efficiency is high. This review perfectly describes the difference between the Baby bullet & the Magic bullet.
If you are looking for a small blender to help you get the job done as quickly as possible, go for the baby bullet. But the magic bullet is more than just a small and efficient mixing machine; it offers a lot more than that – all of which I will show you off with this Blender review. Magic Bullet is a great personal blender that will ensure that you get a smoothie full of all your flavorful nutrients before leaving home to work outside.
The company gets older over the years, so they are developing some of both products’ features. In addition, they are advancing their technology over the year. Both blenders are designing to adopt advanced functionality and easy use at a higher level by the customers.
There are many reasons to get a personal bender. You may need a blander to start diet changes that your dietitian may be advised to stay smooth daily or for any other reason. Both the Magic Bullet and Baby Bullet can be suitable options for you to start your journey.
I like these mixers very much, they are thin and come from the same manufacturer and are very easy to use. They are easy to operate, making them comfortable to handle and place anywhere at your home. This is to evaluate the Magic Bullet vs Baby Bullet review to help you choose which one is better.
Now we are trying to discuss the difference between the Baby Bullet & the Magic Bullet.
Baby BulletCheck Price at Amazon
The selling price of the baby bullet comes to the market at an affordable price. In addition, the baby bullet has the ability to make your baby’s food delicious and usable daily.
Also, making your baby’s food is easy, and there are no preservatives that can harm your baby. So you can easily make your baby food recipes tasty every day. You keep in mind that for every baby food maker, you can use up to 2-3 years.
Baby Bullets is made by the nutribullet company that makes Magic Bullet and Baby Bullet Blenders and designs similarly. The main difference between Baby bullet vs magic Bullet is the accessories.
Pros & Cons
Pros
- Cheerful color and a small smile
- Practical accessories
- Two sizes for mixing
- Nutrient extraction blade
- It comes with a recipe book.
- In additional storage containers
- BPA free
Cons
- It is more limited in function than magic bullets
- Single-speed 200-watt blender base.
- Milling blades for seed, oats, and grain grind.
- Baby mix blade for mixing.
- 32 oz batch bowl for larger recipes.12 oz short cup for short recipes.
- 6 storage cups with a storage lid and date dial.
- Frozen storage container 12 serving (2 oz serving).
- All containers are BPA-free, and jars are dishwasher safe.
- Jars are not recommended to use in a microwave.
To defrost the ingredients, refrigerate the frozen serving or place it in a sealed container in mildly hot water until the elements are soft. The user manual provides a step-by-step guide to the recipes to follow and what foods to use at each stage. It also outlines the general feeding schedule and how to prepare and store baby food.
Making of Natural FoodBaby bullets come in a large mixing bowl and many smaller containers for storing prepared food. This blend allows parents to make natural foods for their babies to ensure no added preservatives. The base is stable and stands on four slightly circular protrusions. Though not as noisy as to treat enough baby food for the whole week, it shelters the powerful motor.
BPA Free & Non-ToxicThis blender is unique because its blades are designed to keep extract nutrients. Of course, you will want your baby to get the most nutrition from the food you make, and this system provides that benefit. In addition, the containers’ bodies are BPA-free and non-toxic, essential in all plastic containers involved with food.
Sometimes you need to make a full batch, and when the big bowl comes in handy other times, you only need to mix a small portion and luckily have a small cup. You can give your child the cup or leave the id icon on the cover when you are done.
Pop Freezer TrayA simple pop freezer tray allows you to store up to 6 portions of baby food that comes with this baby food maker. There’s also a great tray for easy handling, which is a new addition. The whole package is well designed, and the baby food preparation flows admirably.
Magic BulletCheck Price at Amazon
The name Magic Bullet of this device reflects its design brilliantly. The base is strong, the blades are useful, and the container’s ingredients keep natural nutrition. Also, it’s almost magical at the speed of mixing food and drinks. The package includes a 250-watt motor with a stable base housing, an assortment of mugs, variable ids, and a bonus recipe book.
The long cup is what you usually use to mix most foods and drinks. Also, there is a small mug and a party mug. The ids come in a form that seals the cup for a two-to-go drink and has a comfortable lip ring. BPA in plastic containers is free and very durable. The magic bullet provides a seal that helps keep your food and drink for a long time.
Additionally, it is a perfect blender for your baby as a food maker, with a comfortable lip ring on the id for drinking. The 10-second recipe book that Magic Bullet brings is completely inspiring. You can slowly mix some great drinks, but you will find this guide in the recipe book. And the best part is that the blander takes less than a minute to make food for your baby.
Pros & Cons
Pros
- This is a light device
- Aesthetically pleasing design
- It is less price
- The set is easy to clean.
- It does not require too much space to store
- A fully portable two-go cup
- Make fresh & healthy food.
- The blander is BPA free
Cons
- It can only take a limited amount of ice cubes
Performance Test of Baby Bullet vs Magic Bullet
The baby bullet & magic bullet are best for making soft foods and mill grains. While Informatics really does a good job of selling this product, we wanted to see its performance in our own testing. We tested multiple blends using two blades in two blending jars across multiple meals. Our tests looked like we did well on the tested components. We were surprised by the results because a 200-watt motor has enough power to mix the soft elements. We found both are easy to use and have no problem handling blades or jars.
ConclusionThe Magic Bullet is a versatile device. If you’re into smooth and healthy fruit juices, this is the perfect little helper for you. You can use it in your home, or use it. It doesn’t take up too much space, it’s clean and preservative, and you can clean it in a blink of an eye.
Baby Bullets are excellent for making healthy meals and snacks for your baby. It is designed to make your life easier with your small storage cup. Make a batch, freeze it, then pick it up and go.
Magic Bullet and Baby Bullet are both great tools for preparing food for your babies every day. If we choose one, we will go for the Magic Bullet. It is because you can use this blender to make your baby’s food delicious and healthy.
So we want to say baby bullet gives you the best service than the Magic Bullet. So here we are trying to discuss baby bullet vs magic bullet.
Frequently Asking QuestionsWhy will you buy the baby bullet?There are several different baby food manufacturers on the market, and really any blender can make baby food because you mix the soft ingredients. Baby Bullet has everything packaged together and is worth it if you are going to use it. Many people enjoyed using the device and mentioned in the review that it’s easy to use and placeable anywhere on the floor or table. If you need a homogeneous product every day at your home, you can use a basic blender and get a set of small food containers and mix food daily.
Why do you need magic bullets?The magic bullet will help you make fresh juices and foreign drinks in seconds, whether for your own use or even after some of your friends. For example, sauce, spice, and salad dressings are essential for BBQ, and magic bullets can help you get the whip in a few seconds.
Healthy eating often involves polishing fruits and vegetables. Using the magic bullet is perfect for making mixed food before or after your workout, breakfast, luncheon, or even a good night meal. The magic bullet is basically using more and more in the kitchen. This blender allows you to stay organized and healthy during a busy day.
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Saif Nobel
Author at Best Baby Food Maker
Hi, I am Saif Nobel. I’m a Professional Review Blogger. I research various products for clients and my blog visitors. Through my review, I want to help users to select the right product before buying it.
Latest posts by Saif Nobel (see all)
Baby Bullet Vs Magic Bullet: Popular Blender Comparison
Best for Babies | Best for Smoothies |
---|---|
Baby Bullet | Magic Bullet |
Friendly design | #1 selling blender |
Inexpensive | Inexpensive |
BUY NOW | BUY NOW |
Wondering which popular blender is best for making baby food? Let’s compare two popular and affordable options: the Baby Bullet vs. Magic Bullet. The Magic Bullet is one of the most popular and well-designed personal blenders in the world. But is it the best choice for baby food?
The real question everyone wants to know is “do I need a special baby blender?” Or can I just use the Magic Bullet I already have? It’s understandable to question the need for yet another appliance. Especially one that your little ones will eventually outgrow. A Magic Bullet, on the other hand, is more versatile.
To get a better idea of which blender is the best, we need to see which blender is going to be more useful for baby food. Let’s take a look at some of the pros and cons.
Read More: Magic Bullet Not Working – 7 Simple Blender Fixes
Baby Bullet Vs Magic Bullet: Comparison
Baby Bullet Blender
PROS
- Specially Designed for Baby Blending
- 6 Unique Storage Cups + Other Accessories
- Extremely Safe for Infants
CONS
- Not Much Use Outside Baby Food
- Very Weak Motor
Magic Bullet Blender
PROS
- High-Powered Personal Blender
- Comes Included as 13-Piece System
- Under $50
CONS
- Not Ideal for Serious Blending
- Only 250 Watts
Magic Bullet Baby Bullet Baby Care System Review
The Magic Bullet Baby Bullet Baby Care System is an awesome system designed specifically to get your baby the food he or she needs easily and effectively. You can make an entire week of healthy baby food in under 5 minutes by using the Baby Bullet.
Baby food forever!You will not find a better or smarter blender for baby food. However, this is not a high-powered blender that will heat your soup and grind your coffee beans – it is made only for blending nutritious ingredients into easily digestible food for your baby.
Everything that comes with the Baby Bullet is safe. That means the plastic is non-toxic, the plastic is BPA free, and there are no pthalates to be found anywhere.
Read More: Best blender for pureeing baby food
Designed for babiesNot only is this blender great at making the most delicious and healthy baby food ever, but it is also designed to keep babies happy. The six storage cups all have cute smiley faces on them, and even the baby blender itself looks adorable in baby blue.
If you are one of those parents who loves everything about having a baby, I highly recommend the Baby Bullet not only because it can grind carrots and peas into a delicious paste for your baby, but also because it makes feeding your child fun.
Magic Bullet Blender Review
The Magic Bullet Blender is probably one of the cheapest blenders on the market today, but not in quality. This thing costs less than what I spend on coffee in a week. For making personalized shakes and smoothies, it doesn’t get any easier than with the Magic Bullet. It comes as a 13-piece set with a recipe book, special blender cups, and the blender itself.
A little bit of everythingYou can do a bit of everything with the Magic Bullet. When it comes to baby food, you can definitely blend apples in the applesauce, carrots, and peas into a delicious snack for your infant, and even mix in special ingredients for added minerals and nutrients to help your baby grow.
You can also use the Magic Bullet for yourself. It’s great for mixing, blending, and even grinding. This unit is obviously not going to powerfully blend ice into snow with only 250 Watts, but it definitely works for mushing fruits and veggies into a drinkable solution.
Read More: Can You Put Ice in a Magic Bullet? Yes You Can!
Always in a rushIf you are constantly hurrying around, especially with a newborn baby, the magic bullet is a great system to make a quick shake or smoothie in under 5 minutes, then screw on the special to-go lid and head out the door.
Baby Bullet vs Magic Bullet: Main Product Differences
I would have to say the main difference between these two products is strikingly obvious. The Magic Bullet is an all-purpose blender designed for making simple drinks and other blends. Baby Bullet, built by the same company, is very much a baby-only blender designed specifically for baby food.
Different accessoriesThe Magic Bullet comes with adult accessories, special to-go cups, and a recipe booklet to encourage experimentation with different smoothies and juices. Everything is designed for casual blending.
With the Baby Bullet, all of your accessories are tailor made for babies. The cups are adorable with smiley faces and are more similar to sippy cups than to adult drinking cups. This is awesome for babies. Also, everything is a nice baby blue color, making the Baby Bullet excellent for little boys or little girls.
Read More: The best bullet blenders money can buy
But what about power?The power is almost identical. The Magic Bullet has 250 Watts of power while the Baby Bullet has 200 Watts. There is not much of a difference. That said, I would not recommend trying to blend large quantities of ice inside of the Baby Bullet.
And while the power differential is minimal, I would definitely recommend the Magic Bullet for anything larger than a few ounces of non-frozen fruits and veggies. If you are thinking about grinding nuts or other grains, you may find the Baby Bullet leaves chunks behind. If you are wanting a blender that does baby food and normal food, the Magic Bullet will work better.
Baby Bullet vs Magic Bullet: Final ThoughtsHere’s the deal. These blenders are not in the same category. One is not better than the other. These are two very different systems with very different purposes. The Baby Bullet is designed only for babies, to make a full week of healthy baby food that can be stored in the provided cups, which come included with special date dials so that you always know what’s fresh.
Of course, the Magic Bullet can also make one week of baby food, and it can arguably blend better than the Baby Bullet. So, why not buy the Magic Bullet and completely ignore the Baby Bullet?
Well, the same reason you buy a special litter box from the pet store rather than letting your cat do its business in a cardboard box full of sand. When you have a baby, it is nice to have quality products that are made specifically for babies. There is a certain amount of comfort knowing you have the proper equipment to care for your child.
Magic Bullet Creator Collection Series Three 1/7 PVC Action Figure Original Sexy
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10/15/2021 | $ 35,82 | |||
10/16/2021 | $ 35,83 | |||
10/17/2021 | $ 35,83 | 9000 9000 9000 /20$35. 83 | ||
10/19/2021 | $ 35,86 | |||
10/20/2021 | $ 36.09 | |||
10/21/2021 | $ 36.07 | |||
10/22/2021 | $ 36.1 | |||
10/23/2021 | $ 36.07 | |||
10/24/2021 | $ 36.07 | |||
10/25/2021 | $ 36,07 | 9000 9000 900010/2011 10/20 | $36.08 | |
10/27/2021 | $36.14 | |||
10/28/2021 | $ 36.07 | |||
10/29/2021 | $ 36.04 | |||
10/30/2021 | $ 36.05 | 10/31/2011 10/31/2011 10/31/20 | $ 37.94 | |
11/1/2021 | $ 37.94 | |||
11/2/2021 | $ 37.93 | 11/3/2021 | 000 9000 9000 9000 9000 9000 9000 | 2021 |
5/11/2021 | $37.19 | |||
11/6/2021 | $ 37,15 | |||
11/7/7/2021 | $ 37. 15 | |||
11/8/2021 | $ 37.15 | 1111 9001 | 111111 $ 37,19 | |
11/10/2021 | $ 37,22 | |||
11/11/2021 | $ 37.22 | 11/12/2021 | $ 37. | 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9 /13/2021|
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11/17/2021 | $ 37.99 | |||
11/18/2021 | $ 38,06 | 111111/2011 11/19/20 $38,02 | ||
11/20/2021 | $37,98 | |||
11/21/2021 | $37,98 | |||
11/22/2021 | $37,98 | |||
11 /23/2021 | $38.03 | |||
11/24/2021 | $ 37.98 | |||
11/25/2021 | $ 37.99 | |||
11/26/2021 | $ 38 | 11/27/2021 | $ 37. | 111111 28/2021 | $ 37.98 |
11/29/2021 | $ 37.98 | |||
11/30/2021 | $ 37.98 | |||
12/2021 | $ 38 | |||
2/12/2021 | $38.1 | |||
3/12/2021 | $ 38.07 | |||
12/4/2021 | $ 38.1 | |||
12/5/2021 | $ 38.1 | |||
12/6/2021 | $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 $ 38.1 | 12/7/2021 | $ 38.05 | |
12/8/2021 | $ 38,12 | |||
12/9/2021 | $ 38,23 | 11 $38.07 | ||
11/12/2021 | $38.1 | |||
12/12/2021 | $ 38.1 | |||
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12/14/2021 | $ 38,13 | |||
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12/23/2021 | $ 38. 09 | |||
12/24/2021 | $ 38.1 | |||
12/25/2021 | $ 38,11 | 12/2/2011 12/2/20 | $ 38,11 | |
12/27/2021 | $ 38,11 | |||
12/28/2021 | $ 38.09 | |||
12/29/2021 | $ 38,000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 | 30/12/2021 | $38.1 | |
31/12/2021 | $38.08 | |||
01/1/2022 | $38,21 | |||
01/2/2022 | $38,21 | |||
01/3/2022 | $38,21 | |||
01/4/ 2022 | $ 38.18 | |||
01/5/2022 | $ 38.06 | |||
01/6/2022 | $ 38,11 | |||
01/7/2022 | $ 38.1 | |||
01/8/2022 | $38.05 | |||
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01/10/2022 | $ 38,05 | |||
01/11/2022 | $ 38. 08 | |||
01/2022 | $ 38,08 0 | $ 38,13 | ||
01/14/2022 | $ 38,16 | |||
01/15/2022 | $ 38,2 | |||
01/16/2022 | $ 3 | |||
17/01/2022 | $38.2 | |||
18/01/2022 | $ 38.22 | |||
01/19/2022 | $ 38.2 | |||
01/20/2022 | $ 38,24 | |||
01/21/2022 | $ 38,25 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 01/22/2022 | $ 38.28 | ||
01/23/2022 | $ 38,28 | 01/24/2022 | $ 38,28 | 9000 900011 01/25/20 .35 |
01/26/2022 | $38.34 | |||
01/27/2022 | $ 38.39 | |||
01/28/2022 | $ 38,12 | |||
01/29/2022 | $ 38,15 | |||
01/30/2022 9000 9000 9000 9000 9000 9000 9000 | 01/31/2022 | $ 38.15 | ||
02/1/2022 | $ 38,16 | |||
02/2/2022 | 02/3/20 $38.15 | |||
02/4/2022 | $38.15 | |||
02/5/2022 | $ 38,15 | |||
02/6/2022 | $ 38,15 | |||
02/7/2022 | $ 38.15 | 9000 9000 9000 9000 900002/20 $ 38,16 | ||
02/9/922 | $ 38,12 | |||
02/10/2022 | $ 38.14 | 02/11/2022 | $ 38.18 | 9,0004 /12/2022$38.19 |
02/13/2022 | $38.19 | |||
02/14/2022 | $38,19 | |||
02/15/2022 | $38,18 | |||
02/16/2022 | $38,26 | |||
02/17/2022 | $ 38,28 | |||
02/18/2022 | $ 38.3 | |||
02/19/2022 | $ 38.36 | |||
02/20/2022 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 | 02/21/2022 | $38. 36 | ||
02/22/2022 | $ 38.31 | |||
02/23/2022 | $ 38.35 | |||
02/24/2022 | $ 38,42 | |||
02/25/2022 | $ 38,000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 02/26/2022 | $ 38.43 | ||
02/27/2022 | $ 38,43 | |||
02/28/2022 | $ 38.43 | .46 | ||
03/2/2022 | $38.45 | |||
03/3/2022 | $ 38.42 | |||
03/4/2022 | $ 38.4 | |||
03/20/2022 | $ 38,41 | |||
03/6/2022 | $ 38,000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 | 03/7/2022 | $ 38.41 | |
03/8/2022 | $ 38,41 | |||
03/922 | 9000 9000 9000 9000 | 03/2010/2010/20 $38.41 | ||
11/03/2022 | $38. 4 | |||
12/03/2022 | $ 38.31 | |||
03/13/2022 | $ 38.31 | |||
03/14/2022 | $ 38.31 | 03/2022 | 1111 | 03/16/2022 | $ 38,04 |
03/17/2022 | $ 38,22 | |||
03/2022 | 03/2011 03/2011 03/2011 03/2011 03/2011 03/20 $38.15 | |||
03/20/2022 | $38.15 | |||
03/21/2022 | $ 38,15 | |||
03/22/2022 | $ 38.19 | |||
03/23/2022 | 03/2011 03/2011 03/2011 03/20 $ 38.09 | |||
03/25/2022 | $ 38.1 | |||
03/26/2022 | $ 38.14 | 03/27/2022 | $ 38.14 | 9,0004 /28/2022$38.14 |
03/29/2022 | $38.1 | |||
03/30/2022 | $ 38,13 | |||
03/31/2022 | $ 38,21 | |||
04/1/2022 | $ 38,27 | 9000 9000 9000/2022/20$ 38. 15 | ||
04/3/2022 | $ 38,15 | |||
04/4/2022 | $ 38.15 | |||
04/2022 | $ 38.14 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 | 04/6/2022 | ||
04/7/2022 | $38.15 | |||
04/8/2022 | $ 38,15 | |||
04/9/2022 | $ 38,14 | |||
04/2022 | $ 38.14 | 9000 9000 9000/20 | $ 38,14 | |
04/12/2022 | $ 38,12 | |||
04/13/2022 | $ 38.09 | |||
04/2022 | 1111111111111111111111111111111111111AL | 04/15/2022 | ||
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04/17/2022 | $ 38.09 | |||
04/18/2022 | $ 38,09 | |||
04/2022 | $ 43,28 | 04/201222222222 | $ 43.18 | |
04/21/2022 | $ 43.01 | |||
04/22/2022 | $ 42. 76 | |||
$ 42,000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 04/24/2022 | $42.42 | |||
04/25/2022 | $42.42 | |||
04/26/2022 | $ 42.1 | |||
04/27/2022 | $ 42.15 | |||
04/28/2022 | $ 42.07 | $ 41.68 | ||
04/30/2022 | $ 41.86 | |||
05/1/2022 | $ 41.86 | |||
05/2/2022 | $ 4 | |||
05/3/2022 | $41.73 | |||
05/4/2022 | $ 41.73 | |||
05/5/2022 | $ 41.73 | |||
05/6/2022 | $ 280.00 | |||
05/7/2022 | $ 41. $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 411 $ 41. 05/8/2022 | $ 41.35 | ||
05/9/2022 | $ 41. 35 | 05/10/2022 | $ 41.08 | 9000 9000 9000 9000 9|
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05/24/2022 | $41.49 | |||
05/25/2022 | $41,38 | |||
05/26/2022 | $41,2 | |||
05/27/2022 | $40,96 | |||
05/28/ 2022 | $ 41,17 | |||
05/29/2022 | $ 41,17 | |||
05/30/2022 | $ 41,17 | |||
05/31/2022 | 11 $ 4 | |||
06/1/2022 | $41.38 | |||
06/2/2022 | $ 41,27 | |||
06/3/2022 | $ 41. 33 | |||
06/4/2022 | $ 41.41 | |||
06/2022 | $ 4,000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 | 06/6/2022 | $ 41.41 | |
06/7/2022 | $ 41.53 | |||
06/8/2022 | $ 41.33 | $41.26 | ||
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06/12/2022 | $ 41,17 | |||
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06/2022 9000 9000 | $ 40,000 | 06/15/2022 | $ 40.94 | |
06/16/2022 | $ 41.09 | |||
06/2022 | 06/18/2022 | 06/18/2022 | $41.13 | |
06/19/2022 | $41.13 | |||
06/20/20/2022 | $ 41,13 | |||
06/21/2022 | $ 41,23 | |||
06/22/2022 | 06/23/2022 | 06/23/2022 | $ 41,1 | |
06/24/2022 | $ 41,13 | |||
06/25/2022 | $ 41. 18 | 06/26/2022 | $ 41.18 | 9,0004 /27/2022$41.18 |
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10/3/2022 | $ 38. 76 |
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Product name | Magic Bullet Creator Collection Series Three 1/7 PVC Action Figure Original Sexy Female 28cm |
Category | |
Subcategory | |
Pack quantity | |
Original price | US $38. 76 |
Sales price | US $38.76 |
Discount | |
Price in Euro | € |
Item ID | 1005003390 | 4
Updated | October, 3, 2022, Monday, 19:52:12 GMT |
Current time | October 6, 2022, Thursday 18:45:15 GMT |
More information is available on this product page on AliExpress. Go |
In Search of the “Magic Bullet”
Boris Zhukov
What’s New in Science and Technology No. 9, 2005 can't do anything about cancer? I am afraid, however, that the challenges faced by the developers of anti-cancer therapy are not up to the designers of weapons yet. It's the same as if they were offered to create a weapon capable of killing the terrorists who seized the building (and certainly all of them), without damaging the hostages located there.
About a hundred years ago, the chemist and biologist Paul Ehrlich introduced the concept of "magic bullet" into scientific jargon. He called them his dream - a drug that, when introduced into the patient's body, will itself find and kill the causative agent of the disease without harming the patient. Ehrlich immortalized his name by creating such "magic bullets" - sulfonamides, the first effective antibacterial drugs in the history of medicine (which include, in particular, the well-known streptocide). They and antibiotics, which appeared a little later, revolutionized the treatment of infections.
But the enemy they strike is a foreign organism. His enzymes, the chemical reactions that underlie his life, are very different from ours, and you can try to find a substance that is harmless to us, but deadly to him. In addition, it is not necessary to exterminate it to the last cell - it is important to kill the bulk, and our immune system will cope with the few survivors.
What do you want us to do when our own cells attack us? They need the same things for life that we need; whatever is poisonous to them will be poisonous to us. And any of them, having survived, can give rise to a new tumor, quickly nullifying all our efforts.
For a long time, the only treatment for cancer was surgical removal of the tumor. The accumulation of degenerated cells was usually cut out with a large supply of healthy tissue, often the entire affected organ (mammary gland, ovary, etc. ) was removed entirely. Nevertheless, such operations gave only a short respite from death: by the time the patient fell under the surgeon's knife, cells from the tumor, as a rule, had already begun to migrate. It was possible to find out where they had gone only after secondary tumors grew from them. Selective drugs were needed, and in order to create them, it was necessary to find something that distinguishes a cell that has broken off the coils from a healthy one.
One difference was striking: the cancer cell is continuously dividing. Meanwhile, from the first steps of radiobiology, it was known that it is dividing cells that are especially sensitive to radiation. Since the 50s of the last century, radiation therapy has firmly entered the arsenal of clinical oncology - exposure to the affected area of the body with electromagnetic radiation (hard X-rays or gamma rays) or a particle stream. In a sense, the homeopathic principle “treat like with like” was justified: radiation destroys rapidly dividing cells, because during copying their genetic apparatus becomes available to damaging agents. That is, the cell is vulnerable to radiation therapy for the same reason that it turned out to be vulnerable to mutations that led to malignant degeneration. But unlike homeopathy, radiation therapy uses doses that are much higher than the disease-causing ones, and the damage caused by them is incompatible with the life of the cell.
But radiation therapy is a local effect, cells that have migrated from the main tumor, as a rule, do not fall under it. In addition, almost all types of radiation are absorbed in the surface layers of tissues. Therefore, irradiation is effective mainly for the treatment of neoplasms in the skin and other integumentary tissues. There are, of course, special cases. For example, the hormone produced by the thyroid gland requires iodine, and its concentration in this organ is an order of magnitude higher than in any other tissue. Therefore, with thyroid cancer, the patient is fed a radioactive isotope of iodine, which itself concentrates in the right place and infects lawless cells there. But in most cases, radiation therapy of tumors of internal organs is not an easy task.
On the other hand, cytostatic chemicals are free from this restriction, the use of which in the clinic began almost simultaneously with radiation therapy - in the second half of the 40s. The first generation of cytostatics were simply poisons that selectively affected rapidly dividing cells. With such drugs, cancer chemotherapy began, which today has become the most extensive area of clinical oncology.
But not only cancer cells are constantly dividing in the body. Everyone has probably heard that "chemotherapy makes hair come out." That's right: cytostatics are detrimental to the cells of the hair follicles, which must constantly divide in order to ensure hair growth. Of course, when it comes to life and death, you can go without hair for several months. But what about the skin, the top layer of which is constantly dying and sloughing off and must also be continuously renewed? The hematopoietic tissue, the red bone marrow, is also under attack: human red blood cells live only about four months, and in order not to become smaller, precursor cells must divide as usual. However, erythrocytes are given to a person with a huge supply, but a sharp decrease in the number of leukocytes, which also suffer greatly from cytostatics and radiation, can lead to the death of the patient. Therefore, chemotherapy is usually given in cycles with breaks between them to allow the body to repair damaged tissues. (It is clear that in this case, the surviving tumor cells also get a respite.) In especially severe cases, when very high doses of cytostatics are required, the hematopoietic tissue dies completely, and after the drug is removed from the body, the patient has to implant it from the outside - either a donor or a pre-prepared own . One of the oncologists in the hearts compared chemotherapy with the treatment of syphilis used in the Middle Ages with mercury vapor, which almost equally poisoned both spirochetes and their victim. If we recall that the first of the cytostatics was a derivative of the chemical warfare agent - the famous mustard gas, this comparison does not seem so exaggerated.
“In recent years, tremendous changes have taken place in the drug treatment of malignant tumors,” says Vera Gorbunova, head of the Chemotherapy Department of the Russian Cancer Research Center of the Russian Academy of Medical Sciences. “Cytostatics have been replaced by so-called targeted drugs, i.e. targeted drugs created on the basis of new ideas about the process of carcinogenesis developed in previous decades by fundamental science.”
One of the groups of such drugs is monoclonal antibodies, immune proteins that can bind to specific molecules: receptors for growth factors, tyrosine kinases (enzymes that activate intracellular mechanisms of preparation for division), etc. Without directly killing the tumor cell, they fix it at one stage or another of the cell cycle, interrupting the chain of endless divisions and eventually bringing the rebellious cell to apoptosis. Of course, the course of treatment must be repeated from time to time, but a person can live for years and years. And in some cases, the goal of therapy is not the prolongation of the patient's life (even if indefinitely long), but a complete cure.
However, the arsenal of traditional therapy — drug and radiation therapy — in these years was also replenished with new drugs. More recently, the diagnosis of chorionepithelioma meant a death sentence - this tumor, which develops from the remnants of the placenta, i.e. in young women, rapidly metastasizes. But it turned out that she is very sensitive to the drug methotrexate - so much so that the current international standard for specialized oncology clinics includes the requirement of zero mortality from chorionepithelioma. The infamous small cell lung cancer has receded before a number of new drugs (which, by the way, include nitrosomethylurea, which itself is a strong carcinogen). Skin cancers, if treated before they metastasize, can be completely eradicated with modern radiation therapy. And on the wall of the office of the director of the Research Institute of Pediatric Oncology, there are numerous wedding portraits of former patients who came to him in the first years of their lives with terrible diagnoses.
Worth mentioning is the so-called neutron capture therapy, which gives very promising results. This relatively new technology differs from traditional gamma-ray therapy for the better - with it, a narrow beam of thermal "slow" neutrons extracted from the reactor is absorbed by atoms of rare earth elements, which at the same time begin to emit secondary radiation, which, in turn, destroys cancer cells. tumors (for this, a drug containing boron or gadolinium is injected into the tumor before irradiation). Neutrons act only on tumor cells saturated with these elements, so healthy cells practically do not suffer - secondary radiation extends only a few microns. In addition, one session is enough for neutron capture therapy.
And yet, in most cases, seemingly defeated, the tumor returns again and again. Moreover, drugs that once stopped its development, the second time, as a rule, do not work. “The main problem with a malignant tumor is that there are different cells. They have an unbalanced genome, and there are freaks for all occasions. And therefore, no matter what drug we use, there will always be a dozen resistant cells. They gradually multiply, and a tumor appears that is already resistant to this method of treatment,” says Gennady Belitsky, Doctor of Medical Sciences, Head of the Laboratory of Carcinogen Screening Methods at the Research Institute of Carcinogenesis of the Russian Cancer Research Center.
True, among the drugs of the new generation there is a group of drugs that still manage to bypass this vile feature of cancer cells. Back in 1971, the American physician Judah Falkman drew attention to the fact that the rapid growth of a tumor and the formation of metastases begin only after blood vessels grow inside the neoplasm. In the 80s, researchers managed to decipher the chemical signals by which tumors attract capillaries to themselves, and in the 90s, Folkman's employee Michael O "Reilly isolated and identified two substances that suppress this effect. Today, the number of angiostatics - drugs that block the growth of blood vessels , - is measured by many tens, and for some of them it has been proven that there is no decrease in effectiveness with repeated use. The fact is that these substances do not act on malignant cells, but on completely healthy vascular cells that have neither genetic instability nor rapid reproduction - features that allow cancer cells to escape from the action of drugs.Angiostatics have one more plus: in an adult healthy body, the need for laying new capillaries occurs only during pregnancy or regeneration of damaged tissue.In all other cases, the use of angiostatics can damage only tumors, which , having lost its blood supply, not only stops further growth, but it seems to shrink to a much more modest size.
Angiostatic agents are now widely used in the clinic, but it is already clear that they have not become the “magic bullet” that would solve the problem of cancer in general. The enemy of oncologists is too changeable and many-sided, and we owe all the victories over him not only to technologies and methods, but also to ordinary luck.
“Now all the successes in the treatment of tumors are due to the fact that each tumor has its own characteristics, playing on which, you can cut down one of their classes after another,” says Gennady Belitsky.